You can't optimize what you can't measure.
Many of the biological systems that influence how we age, from cellular membranes and mitochondrial function to brain structure, can begin changing before those shifts are obvious day to day.
Routine blood work and conventional MRI provide valuable information. BioMetrix™ is designed to add a deeper layer of biochemical and imaging detail.
A clearer baseline gives you something meaningful to revisit over time.
A deeper view · At a point in time
Your biology is always changing. A baseline helps make those changes visible.
BioMetrix™ captures detailed biochemical and imaging data at a point in time, creating a reference you can return to as time passes.
It begins with measurement.
Measure
BioMetrix™
BioScan
BioScan
A deeper biochemical baseline from one blood draw.
Routine blood panels focus on a familiar set of markers. BioScan adds a deeper view of plasmalogens, phosphatidylcholines, sphingomyelins, ceramides, gastrointestinal tract acids, and other biochemicals studied in aging and metabolic research. Together, these measurements create a detailed snapshot you can revisit over time.
1000+Natural biochemicals assessedIncluding speciated plasmalogens, phosphatidylcholines, sphingomyelins, ceramides, fatty acids, and related biochemical markers.
7TFT-ICR mass spectrometryUltra-high-resolution analysis using the 7 Tesla Ion Cyclotron Resonance platform developed through Dr. Goodenowe’s research program.
1Blood collectionOne collection provides the serum sample used to create a detailed biochemical profile.
How it works
Research-grade mass spectrometry, focused on your baseline.
BioScan uses Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, an ultra-high-resolution analytical technology developed for advanced systems biology research.
Each molecule has a distinct mass signature. FT-ICR-MS can distinguish biochemical species with nearly identical masses, adding detail that routine testing platforms are generally not designed to provide.
From collection to profile
One collection begins a much deeper look at the biochemistry circulating in your blood.
The serum sample is prepared and analyzed on the FT-ICR-MS platform. Its resolution allows BioScan to distinguish individual molecular species that are typically grouped together or not included in routine panels.
The framework
The Four M's of metabolic health.
After decades of research across aging and metabolic biology, these four systems recur as especially informative. BioScan brings them into one view, so each measurement can be understood in context with the others.
M1 · Cellular boundaries
Membranes.
Membranes form the physical boundary of every cell in your body. Their lipid composition is studied in relation to cellular stress, inflammation, and aging. BioScan provides species-level lipidomics that routine consumer testing generally does not include.
- Plasmalogens (PLE/PLC)
- Phosphatidylethanolamines
- Phosphatidylcholines
- Sphingomyelins
- Ceramides
- ω-3 / ω-6 index
- Lysolipids
- GTAs
M2 · Energy & oxidative load
Mitochondria.
Mitochondria produce energy, and oxidative by-products can rise when that process becomes less efficient. BioScan brings mitochondrial phospholipid species together with oxidative-load markers for a more detailed view.
- hsCRP
- Malondialdehyde
- Catalase · SOD
- Galectin-3
- Cortisol
- PE 38:4 · PC 40:4
- Total iron
M3 · The body's build system
Methyltransferase.
Methyl groups support the production of phosphatidylcholine, creatine, neurotransmitters, and many other compounds. BioScan brings markers associated with methylation capacity, throughput, and load into one view.
- Total PE · PC
- Total SM · Ceramides
- Homocysteine
- Creatinine
- PE / PC ratio
- ω-3 / ω-6 ratio
M4 · Muscle & resilience
Muscle & resilience.
Muscle and related biochemical pathways contribute to strength and resilience over time. BioScan brings together creatinine, creatine kinase, peroxisomal pathway markers, and other species associated with tissue maintenance.
- Creatinine
- Creatine kinase
- BUN · Uric acid
- DHA-PE · EPA-PE
- DHA-plasmalogen · EPA-plasmalogen
- Triacylglycerols
BioMetrix™ BioScan Panel
What BioScan measures.
Routine wellness panels provide important information about familiar markers. BioScan adds biochemical species studied in lipidomics, metabolomics, aging, and systems biology research.
Explore an illustrative panel preview, grouped by biochemical system. Select a system to filter the list.
Explore the BioScan panel Hide the BioScan panel
BioMetrix™ BioScan creates a detailed biochemical baseline from one blood collection, reported in a format you can revisit over time.
See
BioMetrix™
NeuroMRI
NeuroMRI
The human brain, digitized in extraordinary detail.
BioMetrix NeuroMRI brings ten advanced MRI sequences together in one research-focused session. High-resolution volumetrics, cortical thickness, white matter microstructure, fiber pathways, cerebral blood flow, vascular reactivity, functional connectivity, and selected metabolite signals are organized into a detailed digital representation of your brain across hundreds of regions. NeuroMRI is optional and available at additional cost.
The idea
Structure. Microstructure. Function. One organized brain profile.
Dr. Goodenowe describes this as the digitization of the human brain. It means translating multiple layers of imaging data into measurements that can be viewed region by region and, when repeated under a consistent protocol, compared over time.
NeuroMRI is not presented as a diagnosis or prediction. It is a detailed observational baseline.
The session
Ten imaging sequences. One multidimensional view.
Each sequence asks a different question of the brain. Together, they describe anatomy, wiring, microstructure, perfusion, vascular response, network activity, and selected metabolite signals.
01
T1-HR
Creates a high-resolution structural map that supports measurements of regional volume and cortical thickness.
02
T2-FSE
Provides fluid-sensitive tissue contrast and maps fluid spaces around and within the brain.
03
T2-FLAIR
Suppresses fluid signal to make differences in white matter signal more visible.
04
T2-SWI
Uses susceptibility-sensitive contrast to visualize venous structures and iron-related signal.
05
DTI
Estimates the direction of water diffusion in white matter to map major fiber pathways.
06
NODDI
Models diffusion signal to estimate neurite density index and orientation dispersion within brain tissue.
07
ASL
Estimates regional cerebral blood flow using magnetically labeled blood water, without injected contrast.
08
rsBOLD
Measures patterns of spontaneous BOLD signal correlation between brain regions at rest.
09
bhBOLD
Observes the BOLD response during a breath hold to estimate cerebrovascular reactivity.
10
MRS
Measures selected metabolite signals within targeted regions of the brain.
The output
A digital brain profile, region by region.
The imaging layers are organized into detailed maps and measurements across hundreds of regions. The report brings complex research data into one coherent view that can be revisited more easily than a collection of separate scan images.
The value of measurement
“You don’t know it if you don’t measure it.”
Dr. Dayan Goodenowe
A baseline you can return to.
A single scan captures one point in time. When NeuroMRI is repeated under a consistent protocol, it provides a structured way to observe differences in your own measurements over time.
It does not promise a particular outcome. It makes more of the brain measurable, organized, and available for longitudinal observation.
For informational and educational purposes only. BioMetrix NeuroMRI is an imaging and assessment service and is not presented as a method for diagnosing, treating, curing, or preventing disease. Individual findings and measurements vary.
The foundation
BioNutrix™
NeuroRestore
NeuroRestore
The human body is a massive biochemical reactor.
BioNutrix™ NeuroRestore approaches nutrition as biochemical engineering. Rather than building a program around one molecule at a time, it organizes more than 50 nutrients, cofactors, phospholipids, amino acids, and other nutritional compounds by the work they support across eight interconnected biochemical systems. The program can then be adapted to the individual and organized for practical daily use.
BioNutrix NeuroRestore · 8 interconnected biochemical systems · 50+ nutrients, cofactors, and nutritional compounds
The supply principle
Biochemistry depends on a continuous supply.
Dr. Goodenowe compares the body to a vast manufacturing system. It cannot store every input indefinitely. It relies on a continuing supply of raw materials, uses them to build biochemical intermediates, and distributes the resulting products throughout the body.
When supply changes, the body adjusts its priorities. That adaptability supports survival, but it does not tell us that every pathway is receiving ideal nutritional input. BioNutrix was created around this systems view: support the pantry, not just one recipe.
Food remains the foundation, but its composition and individual intake vary. BioNutrix does not replace a balanced diet. It provides an organized way to add selected nutrients and cofactors as part of a broader daily program.
The membrane system
Membranes are where cellular function begins.
Plasmalogens are a class of ether phospholipids found in cell membranes and concentrated in the human brain. BioNutrix NeuroRestore includes Dr. Goodenowe’s omega-3 and omega-9 plasmalogen precursors within the membrane-focused portion of the program, along with egg-yolk phosphatidylcholine and other phospholipids, DHA, oleic acid, and vitamins A and E.
The biochemical pantry
Eight systems. One connected biochemistry.
Dr. Goodenowe describes the ingredients as the pantry and the biochemical pathways as the recipes. The value is not any single molecule in isolation. It is how the inputs are organized across systems that overlap and depend on one another.
Membrane system
Omega-9 and omega-3 plasmalogen precursors, egg-yolk phosphatidylcholine and other phospholipids, DHA, oleic acid, and vitamins E and A, organized as inputs for membrane-focused nutrition.
Mitochondrial system
Thiamine, riboflavin, niacin, CoQ10, alpha-lipoic acid, acetyl-L-carnitine, N-acetylcysteine, and ketone bodies, used in pathways associated with cellular energy metabolism.
Methyltransferase system
Methyl-B12, methylfolate, betaine, pyridoxine, N-acetylcysteine, creatine, and phosphatidylcholine, providing methyl donors, cofactors, and substrates used across methyltransferase pathways.
Protein synthesis
Leucine, isoleucine, valine, alanine, glycine, tyrosine, arginine, tryptophan, and cysteine, organized as amino-acid building blocks used in protein synthesis.
Muscle and bone
Creatine, leucine, tyrosine, myo-inositol, and vitamins D3 and K2, selected for their nutritional roles in normal muscle and bone physiology.
Micronutrient foundation
Zinc, magnesium, selenium, copper, manganese, calcium, potassium, molybdenum, chromium, iodine, and iron, essential minerals and trace elements with roles throughout human metabolism.
Carbohydrate utilization
Trehalose, included as a selected carbohydrate source within the broader BioNutrix program.
Antioxidant support
Vitamin C and bisdemethoxycurcumin, included within the antioxidant-focused portion of BioNutrix.
“It’s not just the individual molecules. It’s the protocols. It’s how to put them together.”
Dr. Dayan Goodenowe
Designed for daily use
It has to work in your life.
BioNutrix can begin with a foundational program and then be adjusted for tolerance, preference, schedule, and the broader assessment picture. Ingredients may be organized by day and time of day to make a complex program easier to follow.
Within BioMetrix, BioNutrix provides organized nutritional inputs. BioScan observes biochemical measurements. NeuroMRI provides a separate view of brain structure, microstructure, and function. Together, they create a framework for measuring rather than guessing.
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
About us
We built the system around the science.
BioMetrix begins with the work of Dr. Dayan Goodenowe, PhD, a research scientist and inventor whose work spans high-resolution mass spectrometry, metabolomics, and human biochemistry. His patented work in FT-ICR mass spectrometry and metabolomic data systems helped shape the analytical foundation behind BioScan.
But a powerful instrument is only one part of the work. To turn complex measurements into something people can follow, the surrounding system had to be assembled: sample collection, laboratory processing, imaging access, analysis pipelines, reporting, nutritional tools, and education.
That is the idea behind BioMetrix. It brings different research technologies into one framework so you can establish a baseline, revisit measurements over time, and learn from your own data. The emphasis is on giving you access to objective information and a structured way to follow it over time.
Dr. Goodenowe in the mass spectrometry laboratory
“The objective measurement is just the reality. The reality of the data.”
Dr. Dayan Goodenowe, PhD
Your next step
Bring your biology into view.
BioMetrix gives you access to objective measurements of your biochemistry and brain, creating a personal baseline you can revisit over time.
Start with an assessment or explore a broader program. Choose the path that fits where you are.